Diagnosis of these diseases is important as their identification leads to better blood pressure control and can possibly mitigate the risk of progression of CKD. Recognition of these disorders is important as they are often underdiagnosed which leads to poorer outcomes.Īdrenal disease associated with hypertension in CKD is most commonly due to PA whereas pheochromocytoma and Cushing's disease are important but less common. We outline limitations that advanced kidney disease poses on the diagnostic work up of these disorders and provide a framework for approaching CKD patients suspected of having an adrenal disorder.
Diagnosis of adrenal hypertension and particularly primary aldosteronism (PA) in CKD is frequently not pursued.
This review will focus on hypertension due to underlying adrenal disorders in chronic kidney disease (CKD).
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